Key Takeaways
- Each monthly carton contains 4 single-use 7.2mg auto-injector pens with built-in hidden needles — replacing three separate 2.4mg FlexTouch injections and 12 needles per month.
- Press firmly flat against abdomen, thigh, or upper arm until the yellow bar stops moving and you hear a second click (5–10 seconds); the safety shield locks automatically.
- Store refrigerated (2–8°C), or below 30°C for up to 28 days (vs. 6 weeks for FlexTouch pens); missed doses can be taken within 5 days.
In the Phase 3b STEP UP trial, stepping up from 2.4mg to 7.2mg weekly semaglutide helped adults with obesity reach ~19%–20.7% average weight loss (3). Previously, taking 7.2mg required administering three separate 2.4mg FlexTouch injections every week — now replaced by Novo Nordisk’s single-dose 7.2mg pre-filled auto-injector pen (1,2).
8-step injection checklist for the 7.2mg single-dose pen
- Verify the label reads Wegovy 7.2mg and check the expiration date (especially if you still have older FlexTouch pens in the fridge).
- Inspect the viewing window: liquid must be clear, colorless, and particle-free.
- Select & rotate your site: abdomen, front of thigh, or upper arm.
- Pull off the cap straight: the needle is built in and stays hidden — nothing to screw on.
- Press firmly flat against skin to start injection (watch the yellow indicator bar move and listen for the first click).
- Keep holding firmly for 5–10 seconds until the yellow bar stops moving and you hear the second click — lifting early delivers an incomplete dose.
- Lift straight off skin: the hidden needle guard locks automatically.
- Place the entire single-use pen into a sharps container (never household trash).
Storage & missed-dose rules
- Cold-chain & travel: Store unopened pens at 2°C–8°C in the fridge; if needed for travel, a 7.2mg single-dose pen may stay unrefrigerated below 30°C for up to 28 days (shorter than the 42-day / 6-week allowance on 2.4mg FlexTouch pens) (1,4).
- Missed dose: Take as soon as remembered if within 5 days of your scheduled day; if more than 5 days have passed, skip and resume on your normal weekly schedule (never double-dose).
Questions about GLP-1 dosing? Connect with a clinician via our online consultation.
References
- Novo Nordisk. Wegovy (semaglutide) 7.2 mg single-dose pen — U.S. prescribing information. 2026.
- Novo Nordisk. Wegovy Pen Guide and Dosing Instructions. 2026.
- Wharton S, et al. Once-weekly semaglutide 7.2 mg in adults with obesity (STEP UP)00226-8/abstract). Lancet Diabetes Endocrinol. 2025.
Medical Editorial Review: Reviewed by the Amble Clinical Editorial Team. This article is for educational purposes only and does not replace an individualized consultation with a licensed healthcare professional.
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