Key Takeaways
- Unlike tension headaches—which feel like a dull two-sided band—migraines cause moderate-to-severe pulsating pain (often unilateral) lasting 4–72 hours alongside nausea or light/sound sensitivity.
- Taking acute triptans (sumatriptan, rizatriptan, zolmitriptan, almotriptan) or CGRP blockers (rimegepant) at the earliest onset of head pain maximizes 2-hour pain freedom.
- Consistent sleep, hydration, regular meals, trigger tracking, and preventive therapy (when attacks exceed 4 days/month) protect quality of life.
Migraine vs. Tension Headache: Key Diagnostic Clues
| Feature | Migraine Attack | Tension-Type Headache |
|---|---|---|
| Pain Quality & Location | Moderate-to-severe throbbing or pulsating; often one-sided; worsens with stairs or movement | Mild-to-moderate dull pressure or tight band across both sides of head |
| Associated Symptoms | Nausea/vomiting, photophobia (light), phonophobia (sound), and in ~25% reversible visual/sensory aura | Rarely causes nausea or aura; daily tasks remain manageable |
| Untreated Duration | 4 to 72 hours | 30 minutes to several hours |
Common Triggers & Daily Prevention Habits
Migraine brains dislike sudden change. Frequent triggers include perimenstrual estrogen drops, skipped meals/fasting, dehydration, inconsistent sleep (too little or weekend oversleeping), red wine, aged cheeses/MSG/aspartame, barometric weather swings, fluorescent glare, and let-down periods after intense work stress. Keeping a simple symptom diary plus regular meals, hydration, and aerobic exercise cuts attack frequency measurably.
Comparing Prescription Migraine Treatments
| Medication | Class | Typical Onset & Highlight |
|---|---|---|
| Rizatriptan (Maxalt) | 5-HT1B/1D Triptan (tablet or melt) | Fastest oral triptan—can start relieving pain in as little as 30 minutes |
| Zolmitriptan (Zomig) | 5-HT1B/1D Triptan (tablet, melt, or nasal) | Reliable 1-hour onset; nasal spray bypasses sluggish migraine digestion |
| Sumatriptan (Imitrex) | 5-HT1B/1D Triptan | Most widely studied gold-standard acute triptan; best taken early in headache phase |
| Almotriptan | 5-HT1B/1D Triptan | Favorable tolerability profile for triptan-sensitive patients |
| Rimegepant (Nurtec ODT) | CGRP Receptor Antagonist (Gepant) | Non-vasoconstrictor dissolving tablet used for BOTH acute relief and every-other-day prevention |
Note: Limit acute triptans/NSAIDs to fewer than 10 days per month to avoid medication-overuse headaches, and seek emergency medical care for any sudden explosive ‘thunderclap’ headache, fever, confusion, or persistent weakness.
Medical Editorial Review: Reviewed by the Amble Clinical Editorial Team. This article is for educational purposes only and does not replace an individualized consultation with a licensed healthcare professional.
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